DNA Testing & Pharmacogenetics

Physicians are moving away from the traditional ‘one size fits all’ approach to medical practice. The reason for this is the realization that a person’s genetics determines how they respond to medications. Everyone has a unique genetic make-up. A medication that works perfectly well for one patient may not work for another patient and may be fatal in some cases.

Genetic tests performed on patient’s specimens provide information that physicians can use when prescribing medication. This modern form of medical practice is known as Personalized Medicine. The genetic tests fall under the category of Pharmacogenetic tests. This type of testing is a scientific approach to understanding your genetic make-up to assist your doctor(s) in predicting which medications will work best for you and what is the proper dosage. Your genetic information allows your physician to determine the best match between you and your medication.

CBS Labs uses a simple cheek swab (buccal swab) to collect the DNA sample. It is a pain-less, convenient and needle-free specimen collection procedure. The swab is shipped to CBS Labs for analysis. Analysis of your DNA produces a thorough report allowing your physician to prescribe with confidence so you receive the most effective medication and dosage possible.

CBS Labs leaves clinical decision making to the health care professional by offering specific gene and drug selection and multiple methods of testing based on medical necessity. Our comprehensive testing menus provide an expansive selection of tests to meet the unique needs of individual patients, and health care professionals treating pain, substance use disorders and other psychiatric disorders.

Pharmacogenetic tests can help physicians personalize therapy by choosing the most suitable medications and possibly adjusting standard dosage recommendations. 

The test makes it possible to identify four types of patients:

  • Poor metabolizer with two non-functional alleles.
  • Intermediate metabolizer with one functional allele and one non-functional allele.
  • Extensive metabolizer with two functional alleles.
  • Ultra-rapid metabolizer with more than one increased functional allele.

Knowledge of your patient’s metabolizing rate will allow you to better predict how your patient might respond to certain prescription pain medications.

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